I-Induction, purification and partial characterization

نویسندگان

  • E. MañanÓs
  • S. Zanuy
چکیده

In sea bass (males and non-vitcllogcnic females) estradiol (E2) treatment caused the appcarnnce in the bloodstream of a new protein that was identified as the vitellogenin (VTC) moleculc for this teleost spccies. The molecular weight of the sca bass VTG (445 kDa) and its amino acid composition was similar to that of other teleosts. VTC was purified by doublcstep chromatography and then used to obtain specific antibodies. The localization of VTG in the liver and in the ovary was carried out by immunocytochemistry. The effects of the E2 treatment on the synthetic activity of the liver wcrc studied throughout thc modifications observed at the histological and biochemical levels.

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تاریخ انتشار 2002